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 Vaccinations for those with HIV Infection

The table below gives recommendations on when vaccines can be given 'safely' to those with HIV infection. The advice does not necessarily apply to those with other immunocompromising conditions.

Remember also that vaccines may not always induce a protective response in the immunocompromised.

Note:
The HIV viral load usually increases temporarily following vaccination.
This increase is less if the patient is on effective anti-retroviral therapy. While the clinical significance of this increase is unclear it is prudent to advise vaccinations only when there is a significant infection risk to the traveller.

NOTES ON USING THE CHART BELOW

(1) Double the dose of hepatitis vaccine is recommended in immuno-compromised patients.
(2) Vaccination can be given at the discretion of the clinician in charge if the risk of contracting infection is high.
(3) There have been no reports of any adverse reactions after vaccination against yellow fever. However, there is little experience in HIV positive patients. (4) Oral polio vaccine (OPV) may be given to children who are known to be infected with HIV provided that their household contacts are not immuno-compromised. In these cases inactivated polio

HIV STATUS Symptomatic Asymptomatic
BCG NO NO
CHOLERA yes yes
DIPHTHERIA yes yes
DPT yes yes
HEPATITIS A yes (1) yes (1)
HEPATITIS B yes (1) yes (1)
HUMOTET yes yes
INFLUENZA yes yes
MEASLES yes (2) yes
MENINGO yes yes
MUMPS yes (2) yes
IMMUNOGLOBULIN yes yes
PERTUSSIS yes yes
PNEUMOCOCCAL yes yes
POLIO ORAL yes (2, 4) yes
POLIO INJECT yes yes
RABIES yes yes
RUBELLA yes (2) yes
TETANUS yes yes
TYPHOID(Vi) yes yes
TYPHOID(ORAL) NO NO
YELLOW FEVER caution (2, 3)

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